Imunoistoquímica em oligodendrogliomas

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Pediatric and adolescent oligodendrogliomas.

PURPOSE To review the clinical and imaging findings in pediatric and adolescent intracranial pure oligodendrogliomas. METHODS The clinical, CT, and MR data in 39 surgically proved pure oligodendrogliomas were retrospectively reviewed. RESULTS The frontal or temporal lobes were involved in 32 (82%) cases. Seventy percent of the tumors were hypodense on CT, three-fourths were hypointense on T...

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Current treatment of oligodendrogliomas.

T hat a neurological review is dedicated specifically to the oligodendroglioma is testimony to a decade of progress. The unique molecular features and chemosensitivity of the oligodendroglioma were not appreciated 10 years ago; yet today, these features merit such interest to clinicians and pathologists alike that the oligodendroglioma is separated from other types of primary brain tumors in bo...

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Expression of p53 in oligodendrogliomas.

The expression of the nuclear protein p53 in oligodendrogliomas was investigated by immunohistochemistry, using a monoclonal anti-p53 antibody (DO-7) on formalin-fixed, paraffin-embedded material in 84 histologically verified cases, and compared with the histopathological grade and survival. p53-immunoreactive cells were found in 75 per cent of the samples acquired at the first biopsy. The p53 ...

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Oligodendrogliomas: molecular biology and treatment.

Oligodendroglial tumors continue to receive much attention because of their relative sensitivity to chemotherapy. The histological diagnosis of oligodendroglial tumors is subject to considerable interobserver variation. The revised 2007 World Health Organization classification of brain tumors no longer accepts the diagnosis "mixed anaplastic oligoastrocytoma" if necrosis is present; these tumor...

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ژورنال

عنوان ژورنال: Arquivos de Neuro-Psiquiatria

سال: 2006

ISSN: 0004-282X

DOI: 10.1590/s0004-282x2006000100014